探讨慢性肝炎患者肝癌的患病率及其影响因素.方法 将194例乙肝与丙肝患者依据临床诊断结果进行分组,其中A组为未发展为肝癌的80例乙肝患者,B组为72例乙肝相关性肝癌患者,C组为未发展为肝癌的24例丙肝患者,D组为18例丙肝相关性肝癌患者.采用统一的自行设计的调查问卷对患者进行调查.分析患者由肝炎发展为肝癌的影响因素.结果 饮酒及肝癌家族史与乙肝发展为肝癌呈显著正相关(P＜0 .05或0 .01) ,抗病毒治疗与其呈显著负相关(P＜0 .01).饮酒与丙肝发展为肝癌呈显著正相关(P＜0 .05) ,抗病毒治疗与其呈显著负相关(P＜0 .05) .结论 乙肝和丙肝患者应戒酒,及早并坚持开展抗病毒治疗干预,有肝癌家族史的乙肝患者应警惕肝癌发生风险,注意密切监测和随访,提高患者的生存质量.、Objective To investigate the prevalence of liver cancer in patients with chronic hepatitis and its influencing factors.Methods 194 patients with hepatitis B and hepatitis C were divided according to clinical diagnosis results.80 patients with hepatitis B who did not develop liver cancer were seen as group A ,72 patients with hepatitis B related liver cancer were seen as group B ,24 pa-tients with hepatitis C who did not develop liver cancer were seen as group C ,18 patients with hepatitis C related liver cancer were seen as group D.Patients were surveyed using a unified and self-designed ques-tionnaire.Results There was a significant positive correlation between drinking ,family history of liver cancer and hepatitis B developed into liver cancer (P＜0.05 or 0.01) ,and antiviral therapy was signifi-cantly negatively correlated (P＜0.01).There was a significant positive correlation between drinking and hepatitis C developed into liver cancer (P＜0.05) ,and antiviral therapy was significantly negatively corre-lated (P＜0.05).Conclusion Hepatitis B and hepatitis C patients should abstain from alcohol ,and insist on antiviral therapy intervention early.Hepatitis B patients with a family history of liver cancer should be alert to the risk of liver cancer and pay close attention to monitoring and follow-up to improve the life qual-ity of patients.